MHRA Feb 2019




SGLT2 inhibitors are indicated for the treatment of type 2 diabetes. Medicines in the UK are those containing dapagliflozin, canagliflozin, empagliflozin, and ertugliflozin▼.

Patients taking SGLT2 inhibitors should be advised to seek urgent medical attention if they experience severe pain, tenderness, erythema, or swelling in the genital or perineal area accompanied by fever or malaise. If Fournier’s gangrene is suspected, SGLT2 inhibitor treatment should be stopped and treatment started urgently (including antibiotics and surgical debridement) as appropriate.

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